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1

Synthesis and Evaluation of S- and C(1)-Substituted Analogues of Lincomycin

Marie-Pierre Collin, Sven N. Hobbie, Erik C. Böttger, Andrea Vasella

Journal:

Helvetica Chimica Acta

Year:

2009

Language:

english

File:

PDF, 479 KB

english, 2009

2

Humic substance-mediated Fe(III) reduction by a fermenting Bacillus strain from the alkaline gut of a humus-feeding scarab beetle larva

Sven N. Hobbie, Xiangzhen Li, Mirko Basen, Ulrich Stingl, Andreas Brune

Journal:

Systematic and Applied Microbiology

Year:

2012

Language:

english

File:

PDF, 434 KB

english, 2012

3

Conservation of Bacterial Protein Synthesis Machinery: Initiation and Elongation in Mycobacterium smegmatis †

Bruell, Christian M., Eichholz, Carolin, Kubarenko, Andriy, Post, Virginia, Katunin, Vladimir I., Hobbie, Sven N., Rodnina, Marina V., Böttger, Erik C.

Journal:

Year:

2008

Language:

english

File:

PDF, 671 KB

english, 2008

4

Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket

Katherine S. Long, Jacob Poehlsgaard, Lykke H. Hansen, Sven N. Hobbie, Erik C. Böttger, Birte Vester

Journal:

Molecular Microbiology

Year:

2009

Language:

english

File:

PDF, 284 KB

english, 2009

5

N6′, N6′′′, and O4′ Modifications to Neomycin Affect Ribosomal Selectivity without Compromising Antibacterial Activity

Sati, Girish C., Shcherbakov, Dimitri, Hobbie, Sven N., Vasella, Andrea, Böttger, Erik C., Crich, David

Journal:

ACS Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 633 KB

english, 2017

6

The Molecular Basis for A-Site Mutations Conferring Aminoglycoside Resistance: Relationship between Ribosomal Susceptibility and X-ray Crystal Structures

Peter Pfister, Sven Hobbie, Quentin Vicens, Erik C. Böttger, Eric Westhof

Journal:

Year:

2003

Language:

english

File:

PDF, 300 KB

english, 2003

7

Modification at the 2’-Position of the 4,5-Series of 2-Deoxystreptamine Aminoglycoside Antibiotics to Resist Aminoglycoside Modifying Enzymes and Increase Ribosomal Target Selectivity

Sati, Girish C, Sarpe, Vikram A., Furukawa, Takayuki, Mondal, Sujit, Mantovani, Mathilde, Hobbie, Sven N., Vasella, Andrea, Böttger, Erik C., Crich, David

Journal:

ACS Infectious Diseases

Year:

2019

Language:

english

File:

PDF, 470 KB

english, 2019

8

Epidemiologic, Phenotypic, and Structural Characterization of Aminoglycoside-Resistance Gene aac(3)-IV

Plattner, Michel, Gysin, Marina, Haldimann, Klara, Becker, Katja, Hobbie, Sven N.

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 2.20 MB

2020

9

Predictive Analysis of the Side Chain Conformation of the Higher Carbon Sugars: Application to the Preorganization of the Aminoglycoside Ring 1 Side Chain for Binding to the Bacterial Ribosomal Decoding A Site

Pirrone, Michael Gabriel, Gysin, Marina, Haldimann, Klara, Hobbie, Sven N., Vasella, Andrea, Crich, David

Journal:

Journal of Organic Chemistry

Year:

2020

File:

PDF, 449 KB

2020

10

Modular glycosphere assays for high-throughput functional characterization of influenza viruses

Hobbie, Sven N, Viswanathan, Karthik, Bachelet, Ido, Aich, Udayanath, Shriver, Zachary, Subramanian, Vidya, Raman, Rahul, Sasisekharan, Ram

Journal:

BMC Biotechnology

Year:

2013

Language:

english

File:

PDF, 518 KB

english, 2013

11

Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay

Udayanath Aich, Nia Beckley, Zachary Shriver, Rahul Raman, Karthik Viswanathan, Sven Hobbie, Ram Sasisekharan

Journal:

Year:

2011

Language:

english

File:

PDF, 1.08 MB

english, 2011

12

Structure-Based Design and Synthesis of Apramycin-Paromomycin Analogues. Importance of the Configuration at the 6′-Position and Differences Between the 6′-Amino and Hydroxy Series.

Mandhapati, Appi Reddy, Yang, Guanyu, Kato, Takayuki, Shcherbakov, Dimitri, Hobbie, Sven N., Vasella, Andrea, Böttger, Erik C., Crich, David

Journal:

Journal of the American Chemical Society

Year:

2017

Language:

english

File:

PDF, 583 KB

english, 2017

13

Mutation K42R in Ribosomal Protein S12 Does Not Affect Susceptibility of Mycobacterium smegmatis 16S rRNA A-Site Mutants to 2-Deoxystreptamines

Kalapala, Sarath K., Hobbie, Sven N., Böttger, Erik C., Shcherbakov, Dmitry, Tyagi, Anil Kumar

Journal:

Year:

2010

Language:

english

File:

PDF, 405 KB

english, 2010

14

Synthesis of 1,2,3-Triazole Analogues of Lincomycin

Marie-Pierre Collin, Sven N. Hobbie, Erik C. Böttger, Andrea Vasella

Journal:

Helvetica Chimica Acta

Year:

2008

Language:

english

File:

PDF, 242 KB

english, 2008

15

Neutralization of antibody-enhanced dengue infection by VIS513, a pan serotype reactive monoclonal antibody targeting domain III of the dengue E protein

Budigi, Yadunanda, Ong, Eugenia Z., Robinson, Luke N., Ong, Li Ching, Rowley, Kirk J., Winnett, Alexander, Tan, Hwee Cheng, Hobbie, Sven, Shriver, Zachary, Babcock, Gregory J., Alonso, Sylvie, Ooi, En

Journal:

PLoS Neglected Tropical Diseases

Year:

2018

Language:

english

File:

PDF, 6.77 MB

english, 2018

16

Apralogs: Apramycin 5- O -Glycosides and Ethers with Improved Antibacterial Activity and Ribosomal Selectivity and Reduced Susceptibility to the Aminoacyltranserferase (3)-IV Resistance Determinant

Quirke, Jonathan C. K., Rajasekaran, Parasuraman, Sarpe, Vikram A., Sonousi, Amr, Osinnii, Ivan, Gysin, Marina, Haldimann, Klara, Fang, Qiao-Jun, Shcherbakov, Dimitri, Hobbie, Sven N., Sha, Su-Hua, Sc

Journal:

Journal of the American Chemical Society

Year:

2019

File:

PDF, 601 KB

2019

17

An Advanced Apralog with Increased inâvitro and inâvivo Activity toward Gramânegative Pathogens and Reduced exâvivo Cochleotoxicity

Crich, David, Sonousi, Amr, Quirke, Jonanthan, Waduge, Prabuddha, Janusic, Tanja, Gysin, Marina, Haldimann, Klara, Hobbie, Sven, Sha, Su-Hua, Schacht, Jochen, Christine, Chow, Andrea, Vasella, Bottger

Journal:

Year:

2020

File:

PDF, 1.09 MB

2020

18

Genetic Reconstruction of Protozoan rRNA Decoding Sites Provides a Rationale for Paromomycin Activity against Leishmania and Trypanosoma

Hobbie, Sven N., Kaiser, Marcel, Schmidt, Sebastian, Shcherbakov, Dmitri, Janusic, Tanja, Brun, Reto, Böttger, Erik C., Geary, Timothy G.

Journal:

PLoS Neglected Tropical Diseases

Year:

2011

Language:

english

File:

PDF, 376 KB

english, 2011

19

Preclinical evaluation of VIS513, a therapeutic antibody against dengue virus in non-human primates

Ong, Eugenia Z., Budigi, Yadunanda, Tan, Hwee Cheng, Robinson, Luke N., Rowley, Kirk J., Winnett, Alexander, Hobbie, Sven, Shriver, Zachary, Babcock, Gregory J., Ooi, Eng Eong

Journal:

Antiviral Research

Year:

2017

Language:

english

File:

PDF, 1.74 MB

english, 2017

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